These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of melaxen on free radical processes intensity and some antioxidant enzymes activity in rats liver and blood serum under type 2 diabetes mellitus].
    Author: Verevkin AN, Popova TN, Agarkov AA, Semenikhina AV.
    Journal: Biomed Khim; 2015; 61(5):640-5. PubMed ID: 26539874.
    Abstract:
    The effect of melaxen on free radical processes and activity of superoxide dismutase and catalase in rats with type 2 diabetes mellitus (T2DM) has been investigated. It was established that melaxen administration to diabetic rats caused a decrease of the intensity of free radical processes as evidenced a decrease of the lipid peroxidation primary products content and biochemiluminescence parameters. The activity of the antioxidant enzymes changed towards normal values. These effects were probably induced by the correction of the melatonin level at the result of the melaxen action. Provedeno issledovanie vliianiia melaksena na intensivnost' svobodnoradikal'nykh protsessov i aktivnost' superoksiddismutazy i katalazy u krys s sakharnym diabetom 2 tipa. Ustanovleno, chto vvedenie melaksena pri patologii privodilo k snizheniiu intensivnosti svobodnoradikal'nykh protsessov v tkaniakh zhivotnykh, o chem svidetel'stvuet umen'shenie soderzhaniia pervichnykh produktov peroksidnogo okisleniia lipidov i parametrov biokhemiliuminestsentsii po sravneniiu s gruppoĭ krys s sakharnym diabetom 2 tipa. Pri étom aktivnost' issleduemykh antioksidantnykh fermentov, vozrastaiushchaia pri patologii, izmenialas' v storonu kontrol'nykh znacheniĭ. Nabliudaemye éffekty, veroiatno, sviazany so sposobnost'iu melaksena korrigirovat' uroven' melatonina – gormona, iavliaiushchegosia éffektivnym antioksidantom.
    [Abstract] [Full Text] [Related] [New Search]