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  • Title: SAR-2: identification of a novel plasmid-encoded beta-lactamase from India.
    Author: Nandivada LS, Amyes SG.
    Journal: FEMS Microbiol Lett; 1989 Jan 15; 48(2):219-21. PubMed ID: 2656382.
    Abstract:
    A novel beta-lactamase has been identified in an Escherichia coli strain isolated in South India. The beta-lactamase gene was carried on a plasmid (pUK734) along with resistance determinants to sulphonamides and tetracycline. The novel enzyme has a pI of 8.3 and an Mr of 36,000. The enzyme has a broad-spectrum of activity against both penicillins and cephalosporins. It is also active against oxacillin and methicillin.
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