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  • Title: Primary spinal oligoastrocytoma mimicking longitudinally extensive transverse myelitis.
    Author: Yeo TR, Wong CF, Lee JJ, Ng VZ, Tan K.
    Journal: Mult Scler Relat Disord; 2015 Nov; 4(6):590-3. PubMed ID: 26590667.
    Abstract:
    Longitudinally extensive transverse myelitis (LETM) is most commonly associated with neuromyelitis optica spectrum disorders (NMOSD). However, a wide range of etiologies may produce longitudinally extensive spinal cord lesions (LESCLs) on imaging. We highlight the case of a patient with a spinal cord tumor whose imaging showed LESCL and was diagnosed with LETM. He did not respond to immunosuppression and subsequently developed a progressive and protracted clinical course. Thoracic cord biopsy performed 6 years after symptom onset showed primary spinal oligoastrocytoma. We discuss the features that should raise suspicion of a neoplasm in the context of LESCL and serve a reminder that not all LESCLs are inflammatory.
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