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  • Title: Colon Adenocarcinoma Associated with Synchronous Extramural Gastrointestinal Stromal Tumor (GIST) of the Ileum.
    Author: Gavriilidis P, Nikolaidou A.
    Journal: Am J Case Rep; 2015 Nov 26; 16():837-9. PubMed ID: 26608682.
    Abstract:
    BACKGROUND: GISTs are mesenchymal tumors representing approximately 1% of all gastrointestinal neoplasia. Their concurrence with colorectal cancers is rare. CASE REPORT: We present a case of coexistence of colon adenocarcinoma and GIST of the ileum in a 68-year-old white woman. CONCLUSIONS: The coexistence of mesenchymal and epithelial neoplasia is very challenging; further research is needed to clarify the role of oncogenic mutations and signalling pathways in carcinogenesis of neoplasia of various histiogenic origins.
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