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  • Title: Transrectal fine-needle aspiration and truecut needle biopsy of the prostate: a blinded comparison of accuracy.
    Author: Klotz LH, Shaw PA, Srigley JR.
    Journal: Can J Surg; 1989 Jul; 32(4):287-9. PubMed ID: 2660974.
    Abstract:
    Transrectal needle aspiration biopsy and core biopsy of the prostate were performed simultaneously on 88 men with prostatic nodules. Cytologic and histologic assessments were made in a blinded, independent fashion, and the results were compared. All patients with positive findings on aspiration also had positive findings on core biopsy, for a positive predictive value for aspiration of 100%. However, five negative and six "insufficient" results obtained by aspiration were positive on core biopsy, for a negative predictive value for aspiration of 88%. This experience support the use of needle aspiration as an initial diagnostic maneuver in the assessment of prostatic nodules.
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