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  • Title: Spot Matching of 2-DE Images Using Distance, Intensity, and Pattern Information.
    Author: Xin HM, Zhu Y.
    Journal: Methods Mol Biol; 2016; 1384():109-17. PubMed ID: 26611412.
    Abstract:
    The analysis of a large number of two-dimensional gel electrophoresis (2-DE) images requires developing automatic methods. In such analyses, spot matching plays a fundamental role, in particular for the identification of proteins. We describe a simple and accurate method which allows to automatically and accurately match spots in 2-DE images. The method consists of simultaneously exploiting the distance between the spots, their intensity, and the pattern formed by their spatial configuration.
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