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  • Title: Homology between surface protein antigen genes of Streptococcus sobrinus and Streptococcus mutans.
    Author: Takahashi I, Okahashi N, Sasakawa C, Yoshikawa M, Hamada S, Koga T.
    Journal: FEBS Lett; 1989 Jun 05; 249(2):383-8. PubMed ID: 2661267.
    Abstract:
    The structural gene (pag gene) for a 210 kDa protein antigen of Streptococcus sobrinus serotype g was cloned and compared with that (pac gene) of a 190 kDa protein antigen of Streptococcus mutans serotype c. Immunodiffusion analysis revealed that the product of the pag gene immunologically cross-reacted with that of the pac gene. Southern blot and nucleotide sequence analyses revealed that a significant homology existed between the middle regions of the two structural genes.
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