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Title: Studies on penem antibiotics. II. In vitro activity of SUN5555, a new oral penem. Author: Nishino T, Maeda Y, Ohtsu E, Koizuka S, Nishihara T, Adachi H, Okamoto K, Ishiguro M. Journal: J Antibiot (Tokyo); 1989 Jun; 42(6):977-88. PubMed ID: 2661512. Abstract: The new oral penem antibiotic SUN5555 shows broad antibacterial activity against both aerobic and anaerobic Gram-positive and Gram-negative bacteria. SUN5555 is highly stable against various beta-lactamases. It binds preferentially to the penicillin-binding proteins 2 and 1A of Escherichia coli.[Abstract] [Full Text] [Related] [New Search]