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  • Title: NIR-Remote Selected Activation Gene Expression in Living Cells by Upconverting Microrods.
    Author: Zheng B, Su L, Pan H, Hou B, Zhang Y, Zhou F, Wu X, Gong X, Wang H, Chang J.
    Journal: Adv Mater; 2016 Jan 27; 28(4):707-14. PubMed ID: 26619378.
    Abstract:
    An NIR-controlled gene expression system based on upconverting rods (UCRs) is demonstrated. The UCRs can harvest the "biocompatible" NIR light and convert it into local UV light, resulting in cleavage of the photosensitive molecule (4-(hydroxymethyl)-3-nitrobenzoic acid, ONA) and on-demand release of gene carriers, thus realizing target gene expression at high spatial and temporal resolutions.
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