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  • Title: Extended release of vitamins from magnetite loaded polyanionic polymeric beads.
    Author: Sonmez M, Verisan C, Voicu G, Ficai D, Ficai A, Oprea AE, Vlad M, Andronescu E.
    Journal: Int J Pharm; 2016 Aug 30; 510(2):457-64. PubMed ID: 26626225.
    Abstract:
    Here we explore a novel approach of increasing the release duration of folic and ascorbic acid from magnetite entrapped into calcium-alginate beads. Synthesis and characterization of magnetite-vitamins complexes are reported. The magnetite-vitamins complexes were characterized by FT-IR, XRD, SEM, BET and DTA-TG. Also calcium-alginate magnetic beads were prepared by dripping a mixture of sodium alginate with magnetite-vitamins complexes into calcium chloride solution. Extended release profile of the two experimental models was evaluated and quantified by UV-vis.
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