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  • Title: Promiscuity and pill: etiologic agents in the genesis of cervical malignancy.
    Author: Leppäluoto PA.
    Journal: Acta Cytol; 1977; 21(2):182. PubMed ID: 266326.
    Abstract:
    An 800% increase in the number of "suspicious" Papanicolaou smears from young women have been reported since 1970. In cases diagnosed from tissue specimens as "surface dysplasia," the majority of patients gave histories of use of birth control pills and sexual promiscuity. Sexually active women have an increased incidence of cervical ectopy. In cervical ectopy the endocervical columnar cells are exposed to the acid vaginal content. Development of squamous metaplasia may result. An ideal contraceptive would be one contributing to the preservation of a healthy cervical epithelium without ectopy, and a healthy vaginal content as shown by the presence of Doderlein flora. These conditions would serve to prevent cervical malignancy.
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