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  • Title: Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia.
    Author: Cha MK, Kang CI, Kim SH, Cho SY, Ha YE, Wi YM, Chung DR, Peck KR, Song JH, Korean Network for Study on Infectious Diseases (KONSID).
    Journal: Diagn Microbiol Infect Dis; 2016 Feb; 84(2):102-4. PubMed ID: 26632660.
    Abstract:
    We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially on ST131. Our data suggest that ST131 isolates possessed more virulence traits and showed more multidrug resistance patterns than non-ST131 isolates. Among CTX-M-15 producers, the frequency of serum resistance was significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients with bacteremia.
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