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  • Title: [Paroxysmal nocturnal hemoglobinuria with multiple venous thrombosis and acute renal insufficiency. Description of a case].
    Author: Tedde R, Sechi LA, Marigliano A, Loriga V.
    Journal: Minerva Med; 1989 Jun; 80(6):615-8. PubMed ID: 2664576.
    Abstract:
    Oral anticoagulants were administered to a young woman suffering from P.N.H. after the development of portal vein thrombosis. She interrupted the treatment and developed multiple splanchnic thromboses followed by acute renal failure, from which she recovered four weeks later. Although the pathogenetic mechanism could include renal vascular microthrombosis, the possibility of renal ischemic damage due to massive blood pooling within the splanchnic district is discussed.
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