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  • Title: Pathogenesis and pathology of graft-vs.-host disease.
    Author: Wagner JE, Vogelsang GB, Beschorner WE.
    Journal: Am J Pediatr Hematol Oncol; 1989; 11(2):196-212. PubMed ID: 2665549.
    Abstract:
    Over the past decade, there has been a significant increase in the number of patients with a variety of malignant and nonmalignant disorders referred for bone marrow transplantation. Despite numerous advances in the care of such patients after allogeneic bone marrow transplantation, acute and chronic graft-vs.-host disease continues to be a principal cause of morbidity and mortality. In this article, we will present an overview of the pathogenesis, clinical presentation, and pathological manifestations of these two major complications.
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