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  • Title: Sesquiterpenoids from the roots of Vladimiria muliensis.
    Author: Chen JJ, Bai W, Gobu FR, Wu CH, Zeng J, Sun M, Gao K.
    Journal: J Asian Nat Prod Res; 2015; 17(12):1188-95. PubMed ID: 26675307.
    Abstract:
    An unusual aromadendrane-type sesquiterpenoid with a rare hemiketal-containing 10/3 ring system, named vladimuliecin C (1), and one new eudesmane-type sesquiterpenoid, named vladimuliecin D (4), together with four known sesquiterpenoids, were isolated from the roots of Vladimiria muliensis. The structures of these compounds were elucidated by analysis of spectroscopic data. The absolute configuration of 1 was assigned by X-ray diffraction analysis. A possible biosynthetic process for the formation of 1 is proposed. Compound 1 showed moderate cytotoxicity against three human tumor cell lines.
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