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  • Title: UVEAL MELANOMA EXTENSION TO THE OPTIC CHIASM.
    Author: Abdellatief A, Pulido JS, Bartley GB, Salomao DR, Quinn TA.
    Journal: Retin Cases Brief Rep; 2016; 10(1):1-5. PubMed ID: 26682795.
    Abstract:
    PURPOSE: Case report describing a patient who developed intracranial extension of a uveal melanoma through the optic nerve. METHODS: We reviewed the patient's medical history and images. A 41-year-old woman who was blind in one eye had a uveal melanoma that extended through the optic nerve into the optic chiasm and involved the hypophysis. The patient then developed metastasis. RESULTS: The patient developed uveal melanoma extension into the optic chiasm through the optic nerve resulting in a visual field defect in the fellow eye. CONCLUSION: Uveal melanoma extension through the optic nerve is a devastating complication, which occurs anywhere from 0.6% to 3.7% in patients with uveal melanoma. If enucleation of the affected eye is performed, a representative portion of the optic nerve should be excised to decrease the risk of extension. Patients with phthisical eyes should undergo appropriate imaging techniques to prevent a missed diagnosis of optic nerve involvement.
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