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  • Title: Experience of study of the incidence of malignant neoplasms population in small areas of Ukraine, which suffered contamination with radionuclides due to the Chornobyl accident.
    Author: Prysyazhnyuk AY, Fuzik MM, Gudzenko NA, Bazyka DA, Fedorenko ZP, Ryzhov AY, Sumkina OV, Trotsyuk NK, Khukhrianska OM.
    Journal: Probl Radiac Med Radiobiol; 2015 Dec; 20():229-40. PubMed ID: 26695905.
    Abstract:
    GOAL OF THE STUDY: to evaluate the dynamics of implementation risks of malignant tumors in some small areas of Ukraine in the pre- and post-accident period. MATERIALS AND METHODS: The study population group - the population of the Malyn rayon, Zhytomyr region. The period of observation covered 1980-2014. There was investigated the incidence of malignant tumors in general and individual nosological forms (thyroid cancer, breast cancer, tumors of hematopoietic and lymphoid system). Methods of variation statistics and descriptive epidemiology were used. RESULTS: Characteristics of ionizing radiation influence on the population of Malyn rayon indicate the potential for negative effects, especially for thyroid cancer. Besides the fact that the average total effective radiation dose whole body by radioactive cesium in Malyn rayon population (5.9 mSv) are at medium level in Zhytomyr region and is significantly lower in comparison with those of other areas of the northern part of the oblast, the exposure of thyroid 236 mGy, is significantly higher than the regional figures - 81 mGy. Although the level of morbidity Malyn rayon of malignant tumors in general was about at the national level for 1999-2003 and lower it in the 2012-2014, exceeding the figures of Zhytomyr region, the incidence of thyroid cancer in the 2012-2014 in Malin area was 1.7 times higher in comparison with data for Ukraine and in 1.9 times in comparison with the data in Zhytomyr region. As in most northern areas that fell under radioactive iodine fallouts, there is the realization of increased radiation risk of cancer of this organ. The incidence of breast cancer in female population Malyn rayon is the lowest in comparison with Ukraine and Zhitomir regions. However, the rate of increase in this area is the highest. CONCLUSIONS: The results indicate the need for further monitoring of occurrence of cancer cases in the population of not only Ukraine as a whole, or large administrative units, but also among the population in small areas, taking into account the probability of the realization of risks of radiation-associated disease cases according to local environmental conditions. Meta doslidzhennia: otsinyty dynamiku realizatsii ryzykiv vynyknennia zloiakisnykh novoutvoren' na okremykh malykh terytoriiakh Ukrainy v do- ta pisliaavariinyi periody. Materialy ta metody. Doslidzhuvana populiatsiina grupa – naselennia Malyns'kogo raionu Zhytomyrs'koi oblasti. Period sposterezhennia – 1980–2014 rr. Doslidzhuvalas' zakhvoriuvanist' na zloiakisni novoutvorennia v tsilomu ta okremi nozologichni formy (rak shchytovydnoi zalozy, rak molochnoi zalozy, novoutvorennia krovotvornoi ta limfoidnoi systemy). Vykorystovuvalys' metody variatsiinoi statystyky ta deskryptyvnoi epidemiologii.Rezul'taty roboty. Kharakterystyky vplyvu ionizuiuchogo vyprominiuvannia na naselennia Malyns'kogo raionu svidchat' pro potentsiinu mozhlyvist' negatyvnykh efektiv, osoblyvo shchodo patologii shchytovydnoi zalozy. Poriad z tym, shcho seredni sumarni efektyvni dozy oprominennia vs'ogo tila za rakhunok radiotseziiu naselennia Malyns'kogo raionu (5,9 mZv), znakhodiat'sia na rivni serednikh po Zhytomyrs'ksq oblasti i ie znachno nyzhchymy porivniano z analogichnymy pokaznykamy inshykh raioniv pivnichnoi chastyny oblasti, dozy vnutrishn'ogo oprominennia na shchytopodibnu zalozu, a same 236 mGr, znachno perevyshchuiut' oblasni pokaznyky – 81 mGr. Khocha riven' zakhvoriuvanosti naselennia Malyns'kogo raionu na zloiakisni novoutvorennia v tsilomu buv pryblyzno na natsional'nomu rivni 1999–2003 rr., ta nyzhche za n'ogo v 2012–2014 rr., perevyshchuiuchy pry ts'omu pokaznyky Zhytomyrs'koi oblasti, chastota raku shchytovydnoi zalozy v 2012–2014 rr. u Malyns'komu raioni bula u 1,7 raza vyshchoiu porivniano z danymy po Ukraini ta u 1,9 raza vyshchoiu porivniano z danymy po Zhytomyrs'kii oblasti. Iak i v bil'shosti pivnichnykh raioniv, shcho pidpaly pid diiu opadiv radioaktyvnogo iodu, sposterigaiet'sia realizatsiia pidvyshchenogo radiatsiinogo ryzyku raku ts'ogo organu. Chastota raku molochnoi zalozy u zhinochogo naselennia Malyns'kogo raionu ie nainyzhchoiu porivniano z Ukrainoiu ta Zhytomyrs'koiu oblastiu. Razom z tym, tempy ii zrostannia na tsii terytorii ie naivyshchymy. Vysnovky. Otrymani rezul'taty svidchat' pro neobkhidnist' podal'shogo monitoryngu vynyknennia vypadkiv onkologichnykh zakhvoriuvan' sered naselennia ne til'ky Ukrainy v tsilomu, abo ii krupnykh administratyvnykh odynyts', ale i sered naselennia malykh terytorii, vrakhovuiuchy imovirnist' realizatsii ryzykiv vynyknennia vypadkiv radiatsiino-asotsiiovanykh zakhvoriuvan' vidpovidno do lokal'nykh ekologichnykh umov.
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