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  • Title: Tigroid background in cytology of hyalinizing clear cell carcinoma of the salivary gland.
    Author: Yuan CT, Hsieh MS.
    Journal: Diagn Cytopathol; 2016 Apr; 44(4):338-41. PubMed ID: 26715185.
    Abstract:
    Hyalinizing clear cell carcinoma (HCCC) is a rare and low grade salivary gland carcinoma with a unique recurrent EWSR1 gene translocation. HCCC most commonly arises from intraoral minor salivary glands and its cytological features have not been well evaluated. We report a 28-year-old man with palatal HCCC and emphasize the "tigroid background" and metachromatic matrix observed in scrape cytology. This "tigroid background," usually associated with glycogen-rich clear cell tumors, is an important cytological feature of HCCC. Awareness of this feature can do great help in pathological research and diagnosis.
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