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  • Title: Characterization of a plasmid coding for resistance to broad-spectrum cephalosporins in Salmonella typhimurium.
    Author: Garbarg-Chenon A, Vu Thien H, Labia R, Ben-Yaghlane H, Godard V, Deny P, Bricout F, Nicolas JC.
    Journal: Drugs Exp Clin Res; 1989; 15(4):145-50. PubMed ID: 2673714.
    Abstract:
    Five strains of Salmonella typhimurium isolated from faeces of infants hospitalized at Trousseau Hospital in Paris have been found to be resistant to third-generation cephalosporins. This resistance is by a transferable plasmid-mediated mechanism. The beta-lactamase gene which encodes for an enzyme similar to SHV-2 has been cloned into plasmid pBR322 and expressed in Escherichia coli RR1.
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