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Title: Alectinib Approved for ALK+ Lung Cancer. Journal: Cancer Discov; 2016 Feb; 6(2):115. PubMed ID: 26739884. Abstract: The FDA has approved a third ALK inhibitor, alectinib, for advanced ALK-positive non-small cell lung cancer. Two phase II studies show that patients who have become resistant to crizotinib respond well to alectinib; the drug is also effective against brain metastases, which are common in this disease subtype.[Abstract] [Full Text] [Related] [New Search]