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  • Title: A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site.
    Author: Vestweber D, Brunner J, Baker A, Schatz G.
    Journal: Nature; 1989 Sep 21; 341(6239):205-9. PubMed ID: 2674724.
    Abstract:
    An engineered precursor protein that sticks in the import site of isolated yeast mitochondria can be specifically photo-crosslinked to a mitochondrial outer-membrane protein of relative molecular mass 42,000 (42K). This protein (termed import-site protein 42 or ISP 42) is exposed on the mitochondrial surface; antibodies against it block protein import into mitochondria. ISP 42 is the first identified component of the putative transmembrane machinery that imports proteins into mitochondria.
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