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  • Title: New developments in microextraction techniques in bioanalysis. A review.
    Author: Ocaña-González JA, Fernández-Torres R, Bello-López MÁ, Ramos-Payán M.
    Journal: Anal Chim Acta; 2016 Jan 28; 905():8-23. PubMed ID: 26755133.
    Abstract:
    In recent years, the interest in new extraction methods with lower sample volume requirements, simpler equipment and handling, and lower reagent consumption, has led to the development of a series of microextraction methods based on extraction phases in the microliter order. Nowadays, many references can be found for several of these methods, which imply a wide range of applications referred to both the analyte and the sample nature. In this paper, recent developments in both well-established microextraction techniques (solid phase microextraction, hollow-fiber liquid phase microextraction, dispersive liquid-liquid microextraction, etc.) and recently appeared microextraction procedures (nanoextraction systems, microchip devices, etc.) for the clinical analysis of biological samples will be reviewed and discussed.
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