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  • Title: Incidental finding of multiple well-differentiated papillary mesotheliomas in peritoneum.
    Author: Jakobsen M, Engvad B, Jensen T, Marcussen N.
    Journal: APMIS; 2016 Apr; 124(4):333-4. PubMed ID: 26766140.
    Abstract:
    We present a case of multiple well-differentiated papillary mesotheliomas (WDPM) in the peritoneum found incidentally in a 63-year-old man with urothelial carcinoma of the bladder. When multiple tumors are seen, malignant mesothelioma should be excluded by histopathological examination as this may have a similar focal appearance to WDPM. True stromal invasion is by far the most reliable criterion of mesothelial malignancy. In doubtful cases, a conservative diagnostic approach has been recommended. Compared to malignant mesotheliomas, WDPMs are rare and have a relatively indolent clinical course with a good prognosis. Great care is needed when diagnosing mesothelial proliferations, given the crucial nature of a benign vs malignant diagnosis. No standardized treatment has yet been established.
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