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  • Title: [Evaluation of the efficacy and tolerability of a fixed dose combination of captopril (CPT) 50 mg and hydrochlorothiazide (HCTZ) 15 mg in the elderly].
    Author: Antonicelli R, Raffaelli S, Bossini A, Paciaroni E, Zingaretti P, Botta GF.
    Journal: Riv Eur Sci Med Farmacol; 1989 Apr; 11(2):155-61. PubMed ID: 2678309.
    Abstract:
    In this double blind study we have evaluated the efficacy and tolerability of the association Captopril 50 mg + hydrochlorothiazide 15 mg/die vs hydrochlorothiazide 25 mg/die in aged patients with hypertension. Both drugs showed a good antihypertensive efficacy, and a better efficacy on diastolic blood pressure was shown by the association Captopril + hydrochlorothiazide.
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