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  • Title: [Changes in the rat endocrine pancreas under the effect of urbazon].
    Author: Zafirova M, Zhablenska R, Mikhova Ts, Petkov P, Dochev D.
    Journal: Eksp Med Morfol; 1989; 28(3):35-7. PubMed ID: 2680458.
    Abstract:
    Hypertrophy and hyperplasia of islet tissue, established by morphometry, were proved in the pancreas of rats, treated chronically for a period of 2 months (with urbason-50 mg/kg of body mass). B-cells were granulated. Structures with myelin-like form of membranes were observed in some of them by electron microscope. Mixed islet B-acinar cells were established as well. These data were possibly a morphological expression of stimulating action of urbason on B-cells of Langerhans islets.
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