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  • Title: [Complete Response to Chemotherapy after Resection of Rectal Cancer with Virchow's Lymph Node Metastasis].
    Author: Kuroda K, Nakata B, Nakao S, Lee T, Tendo M, Hori T, Yokomatsu H, Hirakawa K, Ishikawa T.
    Journal: Gan To Kagaku Ryoho; 2015 Nov; 42(12):2282-4. PubMed ID: 26805338.
    Abstract:
    A 62-year-old woman was admitted to our hospital because of bloody stool. Colonoscopy revealed stenosis by a type 2 tumor of the recto-sigmoid colon. A biopsy specimen contained moderately differentiated adenocarcinoma. Thoraco-abdominal computed tomography (CT) showed liver metastasis (S7, 10 mm) and enlargement of Virchow's lymph node (17 mm) and several para-aortic lymph nodes (15 mm on average). Because of oozing from the tumor and severe stenosis of the recto-sigmoid colon, we performed laparoscopic-assisted high anterior resection of the primary lesion. After surgery, 3 courses of mFOLFOX6, 20 courses of mFOLFOX6 plus bevacizumab, and 5 courses of infusional 5-FU plus Leucovorin plus bevacizumab were administered. Thoraco-abdominal CT demonstrated complete response to the 1 year 2 months of chemotherapy. The patient has been alive without relapse for 2 years after surgery.
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