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  • Title: Studies on the pathogenicity of classical enteropathogenic Escherichia coli strains isolated from acute diarrhoea among children 0-5 years of age.
    Author: Ananthan S, Subramanian S, Thyagarajan SP, Jayakumar V, Udayashankar K, Elanchezhiyan M, Shanmugasundaram N.
    Journal: Indian J Pathol Microbiol; 1989 Apr; 32(2):92-100. PubMed ID: 2680935.
    Abstract:
    The mechanisms of pathogenicity in EPEC strains were studied in tissue culture. Escherichia coli was isolated as the predominant organism in the primary culture of 1293 (70.54%) diarrhoeal cases. 284 (90.44%) cases from the age group of 1-6 months showed Escherichia coli as the predominant organism. Classical Enteropathogenic Escherichia coli) were detected in 311 (24.05%) cases. Among EPEC isolates 277 (89.06%) did not produce either LT or ST 32(10.28%) produced LT or ST. 2 strains produced verotoxins belong to serotypes 0:86; K:61, 0:26; K:60, sero groups 0.86 :K:61, 0.142:K 86, 0.128:K 67, 0.126:K 71, 0125:K 70 0119:K69 showed localised adherence and serogroups 0111:K58-055:K59 showed both localised and diffused adherence to HeLa cells.
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