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  • Title: [Treatment of castration-resistant prostate cancer: Evidence-based clinical practice].
    Author: Wang W, Peng RX, Shi GW, Chen SY, Ding Q, He JY.
    Journal: Zhonghua Nan Ke Xue; 2015 Dec; 21(12):1121-4. PubMed ID: 26817307.
    Abstract:
    OBJECTIVE: To introduce the framework of evidence-based practice with a case of castration-resistant prostate cancer (CRPC) as an example. METHODS: A clinical question was formulated according the clinical scenario. A systematic search was conducted for the published literature in the databases of PubMed, EMBASE, Cochrane Library, Clinical Trial Registries, and Web of Knowledge up to Dec 2014. The identified literature was reviewed for quality appraisal before the evidence was applied to clinical practice. RESULTS: The treatment was effective and the patient achieved disease remission. CONCLUSION: Evidence-based practice should be integrated with clinical scenario, current evidence, and patients' willingness, and follow a systematic framework.
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