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Title: Acutifoliside, a novel benzoic acid glycoside from Salix acutifolia. Author: Wu Y, Dobermann D, Beale MH, Ward JL. Journal: Nat Prod Res; 2016 Aug; 30(15):1731-9. PubMed ID: 26820172. Abstract: Ultra high-performance liquid chromatography-mass spectrometry (UHPLC-MS) profiling of a polar solvent extract of juvenile stem tissue of Salix acutifolia Willd. identified a range of phenolic metabolites. Salicortin, 1, a well-known salicinoid, was the major compound present and the study identified young stem tissue of this species as a potential source of this compound for future studies. Three further known metabolites (salicin 2, catechin 3 and tremuloidin 4) were also present. The UHPLC-MS analysis also revealed the presence of a further, less polar, unknown compound, which was isolated via HPLC peak collection. The structure was elucidated by high-resolution mass spectroscopic analysis, 1- and 2-D NMR analysis and chemical derivatisation and was shown to be a novel benzoic acid glycoside 5, which we have named as acutifoliside.[Abstract] [Full Text] [Related] [New Search]