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Title: Silver-Mediated Intermolecular 1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles. Author: Ouyang XH, Song RJ, Hu M, Yang Y, Li JH. Journal: Angew Chem Int Ed Engl; 2016 Feb 24; 55(9):3187-91. PubMed ID: 26823074. Abstract: A new iron-facilitated silver-mediated radical 1,2-alkylarylation of styrenes with α-carbonyl alkyl bromides and indoles is described, and two new C-C bonds were generated in a single step through a sequence of intermolecular C(sp(3)-Br functionalization and C(sp(2))-H functionalization across the alkenes. This method provides an efficient access to alkylated indoles with broad substrate scope and excellent selectivity.[Abstract] [Full Text] [Related] [New Search]