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  • Title: Mast cell differentiation: still open questions?
    Author: Arock M.
    Journal: Blood; 2016 Jan 28; 127(4):373-4. PubMed ID: 26823506.
    Abstract:
    In this issue of Blood, Dahlin et al report on a minor circulating human mast cell (MC) progenitor cell population (lineage-negative [Lin−]/CD34hi/CD117int/hi/high-affinity immunoglobulin E receptor-positive [FcεRI+]), with an immature MC-like appearance, which is present in the peripheral blood (PB) of healthy individuals and of asthma subjects well controlled by treatment or with reduced lung function.
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