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  • Title: [Acute submassive cholestatic hepatitis after treatment with carbimazole. Presentation of a new case and review of the literature].
    Author: Moreno Sánchez D, Medina Asensio J, Colina Ruiz-Delgado F, Campos Cantero R, Crespo Rincón L, Belda Serna A.
    Journal: Rev Esp Enferm Apar Dig; 1989 Sep; 76(3):273-6. PubMed ID: 2682839.
    Abstract:
    Carbimazole, an antithyroid agent of the thioimidazole group, can induce unpredictable liver alterations, presumably by hypersensitivity. We describe the case of a hyperthyroid woman who suffered acute submassive cholestatic hepatitis in the course of treatment with this drug. We also review the other seven cases of carbimazole hepatotoxicity previously communicated in the literature.
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