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  • Title: Synthesis of multi-functionalized benzofurans through the condensation of ninhydrin and phenols using SSA as a recyclable heterogeneous acid catalyst.
    Author: Kundu A, Pramanik A.
    Journal: Mol Divers; 2016 Aug; 20(3):619-26. PubMed ID: 26829938.
    Abstract:
    A simple and efficient one-pot methodology has been developed for the synthesis of biologically important multi-functionalized 3-(2[Formula: see text]-hydroxyaryl)-2-(2[Formula: see text]-carboxyphenyl)benzofurans using silica sulfuric acid (SSA) as a heterogeneous acid catalyst in DMF medium. The significant advantages of this methodology are the use of SSA as a recyclable solid acid catalyst, operational simplicity, easy availability of the starting materials, and good yield of the products with high atom-economy.
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