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  • Title: Lesson of the month 1: Artery of Percheron occlusion - an -uncommon cause of coma in a middle-aged man.
    Author: Bailey J, Khadjooi K.
    Journal: Clin Med (Lond); 2016 Feb; 16(1):86-7. PubMed ID: 26833525.
    Abstract:
    Bilateral paramedian thalamic infarction resulting from artery of Percheron occlusion presents with a distinct clinical syndrome comprising impaired consciousness, often with vertical gaze palsy and memory impairment. This uncommon anatomical variant arises as a single artery supplying both paramedian thalami. Early recognition can be challenging in the obtunded patient, where the differential diagnosis is broad. The acute physician should consider this diagnosis in a patient presenting with unexplained coma so that emergent treatments such as thrombolysis can be employed. Early imaging with computerised tomography can often be normal; therefore the use of magnetic resonance imaging is essential in confirming the diagnosis.
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