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  • Title: Comparison of antiplaque agents using an in vitro assay reflecting oral conditions.
    Author: Evans RT, Baker PJ, Coburn RA, Genco RJ.
    Journal: J Dent Res; 1977 Jun; 56(6):559-67. PubMed ID: 268336.
    Abstract:
    An in vitro assay is described using saliva-treated bovine enamel slabs for determining the potential of chemotherapeutic agents to adsorb to tooth surfaces and act against plaque-forming bacteria. Chlorhexidine was found to inhibit the formation of in vitro plaque by Actinomyces viscosus, A naeslundii, Streptococcus mutans and S sanguis. Actinobolin was found to have marked antibacterial properties but limited adsorptive qualities.
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