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  • Title: [Isoantigens ABH in bladder tumors as an indicator of malignant potential: a combined study with CEA, BMG, Leu-M1 and H-Ag].
    Author: Saegusa M.
    Journal: Hinyokika Kiyo; 1989 Aug; 35(8):1311-21. PubMed ID: 2683647.
    Abstract:
    The author performed immunohistochemical staining of blood group antigen (BGA), CEA, BMG, Leu-M1 and H-Ag on 43 patients with primary superficial bladder tumor to evaluate the malignant potential of bladder tumor. There were no obvious relationships among reactivities to BGA, CEA, BMG, Leu-M1 and H-Ag in identical tissue. Although BGA, CEA and Leu-M1 could be used individually as indicators of malignant potential, of the three, BGA was found to be most useful. Concomitant use of Leu-M1 with BGA might compensate for the disadvantages of BGA alone and make prediction of prognosis more objective. Then, a new evaluation criteria for detecting malignant potential of bladder tumor was proposed.
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