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Title: Giant cell hepatitis with autoimmune hemolytic anemia in a Korean infant. Author: Cho MH, Park HS, Han HS, Bae SH. Journal: Pediatr Int; 2016 Jul; 58(7):628-31. PubMed ID: 26841192. Abstract: Giant cell hepatitis (GCH) with autoimmune hemolytic anemia (AHA) is a very rare disease characterized by early onset and severe clinical manifestations, including immune hemolytic anemia and hepatitis with cholestasis. The prognosis is poor despite aggressive immunosuppressive therapy. We report here the first case of GCH with AHA in East Asia. A 2-month-old boy was admitted with jaundice. Blood test indicated abnormal liver function and low hemoglobin. Direct Coombs test and several autoantibodies associated with liver disease were positive, and liver biopsy was consistent with GCH. He was treated with prednisolone and ursodeoxycholic acid, and at the time of writing was in clinical and biochemical remission after prednisolone was stopped.[Abstract] [Full Text] [Related] [New Search]