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  • Title: Cytogenetic evidence of clonal evolution in 5q- anemia.
    Author: Verhest A, Lustman F, Wittek M, van Schoubroeck F, Naets JP.
    Journal: Biomedicine; 1977 Jul; 27(6):211-2. PubMed ID: 268980.
    Abstract:
    The clinical homogeneity of myeloproliferative syndromes associated with a 5 q- marker can be contested, but nevertheless finds support in the 2 case reports we have cited. One of these observations of refractory anemia with partial myeloblastosis and 5 q- marker has shown a transformation into an acute myelomonocytic leukemia with clonal chromosomal evolution.
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