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  • Title: [Kikuchi-Fujimoto's disease or histiocytic necrotizing lymphadenitis: A report of two familial cases].
    Author: Bakir R, Lecapitaine AL, Chevalier J, Juberthie B, Bouldouyre MA, Gros H.
    Journal: Rev Med Interne; 2016 Nov; 37(11):771-774. PubMed ID: 26907374.
    Abstract:
    INTRODUCTION: The histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoto's disease is characterized by a lymph node inflammation whose similarity with systemic lupus is generally admitted. CASE REPORT: Our description of two familial cases aims at raising the hypothesis of the existence of a genetic background in this disease following the example of what is observed in the autoimmune diseases. CONCLUSION: Pathophysiology of Kikuchi-Fujimoto's disease is probably multifactorial and may include predisposing genetic background and a possible infectious triggering event.
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