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  • Title: 18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors.
    Author: Morana G, Piccardo A, Garrè ML, Cabria M, Rossi A.
    Journal: Clin Nucl Med; 2016 Jul; 41(7):e351-2. PubMed ID: 26909711.
    Abstract:
    We report the finding of increased F-3,4-dihydroxyphenylalanine uptake of the brain parenchyma adjacent to developmental venous anomalies, incidentally discovered in 3 pediatric patients with diffusely infiltrating gliomas. One patient presented 3 developmental venous anomalies located distant from the tumor, whereas in the remaining 2 patients, the vascular anomalies were inside the tumoral area mimicking a focal area of increased tumor metabolism. In the setting of brain tumor imaging, focal increased F-3,4-dihydroxyphenylalanine uptake should be carefully interpreted in light of MRI findings, and nuclear medicine physicians should be aware of any incidental minor vascular abnormality for proper interpretation of PET data.
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