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  • Title: Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes.
    Author: Tsyganov DV, Krayushkin MM, Konyushkin LD, Strelenko YA, Semenova MN, Semenov VV.
    Journal: J Nat Prod; 2016 Apr 22; 79(4):923-8. PubMed ID: 26910798.
    Abstract:
    Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill, and parsley. The target 1-arylalkoxynaphthalenes (5) exhibited antiproliferative activity in a phenotypic sea urchin embryo assay.
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