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  • Title: Prescriber compliance with renal function monitoring in patients taking dabigatran (Pradaxa).
    Author: Thorne K, Dee S, Jayathissa S.
    Journal: N Z Med J; 2015 Dec 04; 128(1426):83-8. PubMed ID: 26913911.
    Abstract:
    AIM: To assess whether patients prescribed dabigatran had their renal function monitored in accordance with published guidelines. METHODS: We recruited patients from Hutt Hospital and two large primary care practices if they were prescribed dabigatran between July 2011 and April 2012. We assessed patients prescribed dabigatran for more than a year to ascertain whether renal function was monitored at least annually, in keeping with guidelines. RESULTS: All patients had baseline renal function testing. At baseline, 42 (60%) had an eGFR (estimated Glomerular Filtration Rate) over 60mL/min/1.73m2 and 28 (40%) had eGFR between 30-60mL/min/1.73m2. Median follow up was 46 months. Whilst taking dabigatran, 44 of the 70 patients (63%) had at least annual renal function. CONCLUSIONS: Over one-third of patients taking dabigatran for over a year did not have their renal function monitored in keeping with current guidelines, potentially leading to an increased risk of bleeding. We suggest there is a need for an automated reminder to prompt annual renal function testing.
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