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Title: Applications of spectroscopy in diagnosis, staging, and treatment of urologic malignancies. Author: Seltz LM, Herrell SD. Journal: Curr Opin Urol; 2016 May; 26(3):259-63. PubMed ID: 26914060. Abstract: PURPOSE OF REVIEW: To review the scientific literature on clinical applications of spectroscopy within urologic oncology. Specifically, we address the role of spectroscopy as a novel intraoperative or intraprocedural modality for the management of urothelial carcinoma, renal cell carcinoma, and prostate adenocarcinoma. RECENT FINDINGS: Recent studies have demonstrated that spectroscopy models, suitable for translation to in-vivo clinical use, can differentiate between benign parenchyma and malignant tissue for urothelial carcinoma, renal cell carcinoma, and prostate adenocarcinoma. Recent work has also established spectroscopy as a feasible modality to detect biologically aggressive high-risk disease and classify natural biomarkers. SUMMARY: Spectroscopy has the ability to objectively diagnose and stage malignancies in real time without tissue or cellular disruption. In the future, additional in-vivo studies will be needed to demonstrate that current models remain robust under physiological conditions.[Abstract] [Full Text] [Related] [New Search]