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  • Title: Three New Sesquiterpenoids and One New Sesquiterpenoid Derivative from Chinese Eaglewood.
    Author: Zhao H, Peng Q, Han Z, Yang L, Wang Z.
    Journal: Molecules; 2016 Feb 27; 21(3):281. PubMed ID: 26927050.
    Abstract:
    Three new sesquiterpenoids (1-3) and one new sesquiterpenoid derivative (4), along with three known sesquiterpenoids (5-7), were isolated from the 95% ethanolic extract of Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. The structures of these compounds were elucidated through extensive analysis of spectroscopic data including IR, NMR, HRESIMS, and X-ray diffraction experiments. In addition, the above new compounds were detected for their bioactivities against LPS-induced NO production in RAW 264.7 cells. Among them, compound 2 exhibited obvious anti-inflammatory activity with an IC50 value of 8.1 μM.
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