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Title: Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010. Author: Liu Z, Chen Y, Chen S, Liu Y, Lu Y, Chen D, Lin Y, Huang X, She Z. Journal: Org Lett; 2016 Mar 18; 18(6):1406-9. PubMed ID: 26938636. Abstract: Two new sesterterpenoids, aspterpenacids A (1) and B (2), with an unusual carbon skeleton of a 5/3/7/6/5 ring system were isolated from the mangrove endophytic fungus Aspergillus terreus H010. Their structures were elucidated on the basis of spectroscopic methods, single-crystal X-ray diffraction analysis, and electronic circular dichroism calculations. A biogenetic pathway for 1 and 2 is proposed. Both 1 and 2 showed no significant antibacterial activity or cytotoxicity at 50 μM.[Abstract] [Full Text] [Related] [New Search]