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  • Title: Myritonines A-C, Alkaloids from Myrioneuron tonkinensis Based on a Novel Hexacyclic Skeleton.
    Author: Li XH, Zhang Y, Zhang JH, Li XN, Cao MM, Di YT, Peng ZG, Jiang JD, Hao XJ.
    Journal: J Nat Prod; 2016 Apr 22; 79(4):1203-7. PubMed ID: 26967892.
    Abstract:
    Myritonines A-C (1-3), three new alkaloids bearing an unprecedented heterohexacyclic skeleton, were isolated from Myrioneuron tonkinensis. Their structures were determined by a combination of spectroscopic data and single-crystal X-ray diffraction analysis. Compound 3 represents the first Myrioneuron alkaloid featuring a unique trans-decahydroquinoline motif and was also found to possess a rare cyano functionality. Compounds 1 and 2 showed inhibition against the hepatitis C virus in vitro.
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