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  • Title: Chemical constituents from rhizome of Anemone amurensis.
    Author: Lv CN, Li YJ, Wang J, Qin RL, Lei TL, Lu JC.
    Journal: J Asian Nat Prod Res; 2016 Jul; 18(7):648-55. PubMed ID: 26978669.
    Abstract:
    Phytochemical investigation of the 70% EtOH extract of the rhizome of Anemone amurensis led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR data, and HR-ESI-MS. Compounds 1 and 2 were tested for cytotoxicities against two human cancer cell lines (A549 and Hep-G2). Compound 2 showed potent cytotoxicity with IC50 values of 38.53 and 66.17 μM, respectively, while compound 1 with IC50 > 100 μM.
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