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  • Title: Does membrane-associated DNA play a role in the establishment of hormonal imprinting in the unicellular Tetrahymena?
    Author: Csaba G, Darvas Z, László V, Kovács P.
    Journal: Cytobios; 1989; 60(242-243):171-6. PubMed ID: 2698782.
    Abstract:
    Treatment of Tetrahymena with DNase considerably reduced the FITC-insulin binding capacity of the unicellular organism, but a normalization of the binding value followed after 24 h. DNase equally prevented imprinting in Tetrahymena when applied before or after insulin. It appears that membrane-associated DNA plays an important role in the hormone binding of Tetrahymena, and also presumably in the development and/or stabilization of hormonal imprinting.
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