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  • Title: Rewiring Cas9 to Target New PAM Sequences.
    Author: Siksnys V, Gasiunas G.
    Journal: Mol Cell; 2016 Mar 17; 61(6):793-4. PubMed ID: 26990984.
    Abstract:
    Papers by Anders et al. (2016) and Hirano et al. (2016b), published in this issue of Molecular Cell, show that SpCas9 uses an induced fit mechanism to recognize altered protospacer adjacent motif (PAM) sequences.
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