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  • Title: Synthesis of benzimidazole derivatives as potential antimicrobial agents.
    Author: Habib NS, Abdel-Hamid S, el-Hawash M.
    Journal: Farmaco; 1989 Dec; 44(12):1225-32. PubMed ID: 2699417.
    Abstract:
    Three novel series of benzimidazol derivatives were prepared. Namely; 2-alkyl-1-(4-substituted-4H-1,2,4-triazole-5-thion-3-yl)methylb enzimidazoles; 2-alkyl-1-(5-substituted amino-1,3,4-thiadiazol-2-yl)methylbenzimidazoles; and 2-alkyl-1-[(3,4-disubstituted thiazolin-2-ylidene)hydrazinocarbonyl] methylbenzimidazoles. The antimicrobial testing of the prepared compounds as well as of the key intermediate thiosemicarbazides was performed.
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